T cells stop to smell the (antigenic) roses.

Stop and Smell the Roses: Inostensible Propositional Knowledge and Raising the Standard of Knowing

The represented objects of olfactory experience: Everyday objects and bare olfactory objects

This paper aims to identify the represented objects of olfactory experiences, i.e., what it is that olfactory experiences represent as being “smelly”. I argue that there are two types of olfactory experiences: attached smell experiences, in which smells are experienced as qualifying particular everyday objects, like roses, garbage bins, and cakes baking in the oven, and lone smell experiences, ...

Real-time sensing of roses' aroma using an odor sensor of quartz crystal resonaotors

In order to detect plant aroma in a natural environment, we have investigated roses’ aroma using an odor sensor of quartz crystal resonator (QCR). In present work, we describe experimental setup for real-time sensing of roses’ aroma and feature extraction of roses’ aroma sensed by QCR sensors. This method can distinguish as different aroma as human sense of smell judged for two kinds of roses. ...

Recent Advances in T Cell Signaling in Aging

The immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. Well characterized are age related defect in T cell functions and cell mediated immunity. Although it is well established that the functional properties of T cells decrease with age, its biochemical and molecular nature is...

Activation-Induced Apoptosis in T cells: Effect of Age and Caloric Restriction

We have previously shown that the proliferative response of T cells to antigenic or mitogenic stimulus decreased with age and that caloric resection (CR) attenuated the age-related decline in proliferation and IL-2 expression. Because activation-induced apoptosis is known to regulate cell proliferation and eliminate the high number of activated cells during an immune response, it was of interes...